Some people report changes in mood or anxiety while on GLP-1 medications. Understanding the relationship between these medications and mental health can help you make informed decisions and know when to seek support.
What the Research Shows
- • No consistent link between GLP-1s and increased anxiety
- • Some people report improvement in mood (likely weight-loss related)
- • Others report temporary mood changes during adjustment
- • Rapid lifestyle changes can affect mental health
Possible Causes of Mood Changes
Hormonal Shifts
Rapid weight loss affects hormone levels, including those that regulate mood. This is usually temporary as the body adjusts.
Blood Sugar Fluctuations
Changes in blood sugar can affect mood and energy. Eating regular, balanced meals helps stabilize blood sugar levels.
Relationship with Food
If you've used food for emotional comfort, reduced appetite may feel unsettling at first. This adjustment is normal but worth discussing with a professional if difficult.
Physical Side Effects
Dealing with nausea, fatigue, or other side effects can increase stress and affect mood temporarily.
Managing Mental Health on GLP-1s
Maintain Support Systems
Stay connected with friends, family, or support groups. Weight loss journeys can be emotional, and support helps.
Continue Mental Health Treatment
If you're already seeing a therapist or taking medication for anxiety, continue treatment and inform your provider about starting GLP-1s.
When to Get Help
Contact your healthcare provider if you experience persistent anxiety, panic attacks, depression, or thoughts of self-harm. These warrant immediate attention.
The Bottom Line
GLP-1 medications don't consistently cause anxiety, but the lifestyle changes they enable can affect mood. Monitor your mental health, maintain support systems, and communicate with your healthcare providers about any concerns.