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Managing Fatigue on GLP-1 Medications

Rx Saver Hub TeamDecember 5, 20258 min read
Person managing energy levels during weight loss

Fatigue is reported by some people starting GLP-1 medications, especially during the initial weeks. Understanding the causes and solutions can help you maintain your energy levels during treatment.

Common Causes of Fatigue

  • • Reduced calorie intake (your body is adjusting)
  • • Dehydration from GI side effects
  • • Blood sugar changes
  • • Nutrient deficiencies from eating less
  • • Poor sleep from lifestyle changes

Strategies to Boost Energy

Prioritize Protein

Protein provides sustained energy. Aim for 60-100g daily, even with reduced appetite. Start meals with protein to ensure you get enough.

Stay Hydrated

Dehydration is a major cause of fatigue. Aim for 8+ glasses of water daily. Add electrolytes if you've had GI issues.

Don't Skip Meals

Even if not hungry, eat small, regular meals to maintain blood sugar and energy. Extreme calorie restriction leads to fatigue.

Consider a Multivitamin

Eating less can lead to vitamin deficiencies. A daily multivitamin, especially with B vitamins and iron, can help maintain energy.

Light Exercise

It seems counterintuitive, but light activity like walking can actually boost energy levels. Start slow and listen to your body.

When Fatigue May Indicate a Problem

See your doctor if fatigue is:

  • • Severe or debilitating
  • • Getting worse over time
  • • Accompanied by other symptoms (dizziness, rapid heartbeat)
  • • Not improving after several weeks

The Bottom Line

Fatigue on GLP-1 medications is usually temporary and related to reduced calorie intake and adjustment period. Prioritize protein, hydration, and regular meals. Most people find their energy improves as their body adapts.

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Medical Disclaimer: This article is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare provider before starting any weight loss treatment or if you experience symptoms of gallbladder problems. Individual results and risks may vary.