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#124

SynergyRx Review

All 50 states and a $100 welcome credit — but GLP-1 pricing is not published

7.2/10
Good
7.2/10

GLP-1 pricing not published; NAD+ and peptide injections from $275, B12 from $109

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Overview

SynergyRx offers compounded semaglutide and tirzepatide alongside brand-name FDA-approved options, with telemedicine available in all 50 states subject to each state's prescribing rules, and a $100 welcome credit applied automatically at checkout. Its adjacent injectables are priced openly — NAD+, sermorelin, glutathione and PT-141 from $275, B12 methylcobalamin from $109 — and it describes ongoing support through monthly check-ins and messaging. Its FAQ content is unusually substantive for this market, explaining what GLP-1 medications are, how titration works, and stating that compounded formulations come through licensed US compounding pharmacies. What is missing is the number that matters most: the monthly cost of the GLP-1 programme itself is not published, which for a treatment taken over many months is the central piece of information.

Pros

  • Available in all 50 states subject to state prescribing rules
  • $100 welcome credit applied automatically at checkout
  • Both compounded and brand-name FDA-approved options
  • Monthly check-ins and messaging access included
  • Adjacent injectable pricing published openly — NAD+ from $275, B12 from $109
  • Substantive educational FAQ content rather than pure sales copy

Cons

  • GLP-1 monthly pricing is not published on public pages
  • NAD+ and peptide injections at $275 are at the expensive end of that market
  • Compounding pharmacy not named and 503A versus 503B status unstated
  • No lab work described as part of the programme
  • Compounded medications are not FDA-approved as finished products

Key Features

Compounded Semaglutide and Tirzepatide
Brand-Name FDA-Approved Options
All 50 States
Monthly Check-ins and Messaging
$100 Welcome Credit

Best For

Patients who want 50-state availability and both compounded and brand-name options, and will request full pricing first

SynergyRx at a Glance

Everything below reflects what SynergyRx published on its own site as of August 24, 2026. Where a detail is not published, we say so rather than guessing.

Medications offered
  • Compounded semaglutide
  • Compounded tirzepatide
  • Brand-name FDA-approved GLP-1 medications
  • NAD+ injection
  • Sermorelin injection
  • Glutathione injection
  • B12 methylcobalamin
  • PT-141
Brand-name or compounded
Both. SynergyRx states that compounded formulations come through licensed US compounding pharmacies complying with FDA and state regulations, and that brand-name FDA-approved medications are also available. Compounded medications are not FDA-approved as finished products.
Consultation process
Online intake with licensed provider review of medical history to determine whether GLP-1 therapy is appropriate, followed by monthly check-ins and messaging access.
Eligibility
The provider reviews medical history to determine suitability. Specific BMI thresholds are not published.
Provider involvement
Licensed providers prescribe, tailor dosing and titration, and provide ongoing support through monthly check-ins and messaging. Individual clinicians are not named.
Lab requirements
Not published on SynergyRx's website at the time of review. Confirm directly with SynergyRx before enrolling.
Pharmacy fulfillment
Described as licensed US compounding pharmacies complying with FDA and state regulations. Individual pharmacies are not named and 503A versus 503B status is not stated.
Shipping
Discreet shipping, described as included.

Pricing

SynergyRx does not publish the monthly cost of its GLP-1 programme on public pages, which is the single most important number for a treatment taken over many months. Its adjacent injectables are priced openly — NAD+, sermorelin, glutathione and PT-141 from $275, B12 methylcobalamin from $109 — and a $100 welcome credit is applied automatically at checkout. Before signing up, ask for the monthly GLP-1 cost at the starting dose and at the maximum dose, whether there is a separate consultation or membership fee, and what the cancellation terms are.

Membership fees

Not published on SynergyRx's website at the time of review. Confirm directly with SynergyRx before enrolling.

Medication fees

  • GLP-1 programme pricing not published
  • NAD+, sermorelin, glutathione, PT-141: from $275
  • B12 methylcobalamin: from $109
  • $100 welcome credit applied at checkout

Prices change often in this category. Always confirm the current cost — including what you will pay after any introductory or promotional period — directly with SynergyRx before enrolling.

Cancellation, Refunds & Payment

Cancellation policy
Not published on SynergyRx's website at the time of review. Confirm directly with SynergyRx before enrolling.
Refund policy
Not published on SynergyRx's website at the time of review. Confirm directly with SynergyRx before enrolling.
Insurance
Not mentioned; pricing is presented as cash-pay.
HSA / FSA
Not published on SynergyRx's website at the time of review. Confirm directly with SynergyRx before enrolling.

Support Services

Monthly check-ins
Messaging access to the care team
Dose titration guidance
Adjacent injectable therapies available

Limitations to Know

  • GLP-1 pricing unavailable without going through intake
  • Pharmacy unnamed; 503A versus 503B status unstated
  • Cancellation and refund terms not published
  • No lab monitoring described
  • Compounded products are not FDA-approved as finished drugs

Alternatives to SynergyRx

HealthRX

Publishes full pricing from $99/month across all 50 states, with 503A status stated explicitly.

CareBareRX

Flat $199/month published at every dose, with the thyroid safety warning stated on its own pages.

SnagRx

$69 semaglutide and $119 tirzepatide published openly with a refund if not approved.

Still comparing? See our full ranking of online GLP-1 providers.

SynergyRx FAQs

How much does SynergyRx cost?

GLP-1 pricing is not published on its public pages. Adjacent injectables are — NAD+, sermorelin, glutathione and PT-141 from $275, B12 from $109 — and a $100 welcome credit applies at checkout. Ask for the monthly GLP-1 cost at the starting and maximum dose before providing payment details.

Is SynergyRx available in my state?

It states telemedicine availability in all 50 states, subject to each state's telehealth and prescribing regulations. That is broader coverage than several competitors, which exclude a handful of states.

Is $275 reasonable for an NAD+ injection?

It is at the expensive end. More importantly, there is no established evidence that NAD+ supplementation improves weight-loss outcomes on a GLP-1, so treat it as a separate purchase decision rather than part of the weight-loss programme, and ask what evidence supports it.

Does SynergyRx offer brand-name medication?

It states that providers may prescribe semaglutide or tirzepatide including FDA-approved brand-name medications. If you go that route, check your insurance formulary and manufacturer-direct self-pay programmes first — both frequently beat cash pricing through telehealth.

Date reviewed: August 24, 2026

Sources consulted

Medical disclaimer: This review is for educational and comparison purposes only and is not medical advice. Rx Saver Hub is not a medical provider and does not prescribe medication. Compounded medications are not FDA-approved, and the FDA does not evaluate their safety, effectiveness or quality. Program details, pricing and availability change frequently — verify everything directly with SynergyRx. Always consult a qualified healthcare provider before starting, stopping or changing any weight-loss treatment. Individual results vary.

SynergyRx

7.2/10

GLP-1 pricing not published; NAD+ and peptide injections from $275, B12 from $109

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Brand-name & compounded options

Quick Stats

Rank#124 of 133
Rating7.2/10
PricingGLP-1 pricing not published; NAD+ and peptide injections from $275, B12 from $109

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