Cheapest GLP-1 Programs Actually Compared
Almost every GLP-1 program advertises a low starting price, and almost none of them mean it for long. Introductory rates expire, memberships are charged separately, and prices climb as you titrate to a maintenance dose. This guide compares what these programs really cost over a year — not what the landing page says in month one.
The Quick Answer
OurView Health publishes the lowest price we found — $75/month for compounded semaglutide — though consultations are $97 unless you hold a membership it does not price publicly. Trimi Health is the cheapest program where the headline number is genuinely the whole bill, at $99/month all-in. OrderlyMeds has the lowest entry price at $74 for the first month and honestly publishes the $149 renewal rate. If a GLP-1 is not essential, Nurx's oral options start at $15/month.
Also see our full GLP-1 cost guide for the total annual picture.
FDA actions affecting a provider on this page
FDA has issued warning letters to telehealth companies over false or misleading claims about compounded GLP-1 products. One provider ranked on this page received one. A warning letter is FDA's stated position that violations occurred — not a court finding, a recall, or a determination that any patient was harmed — and companies often correct the cited material.
- OrderlyMeds — FDA warning letter, June 8, 2026 (MARCS-CMS 728291). Read it on fda.gov →
We keep these providers listed because their published details are still worth comparing, and we disclose the action so you can weigh it yourself. You can search any company in FDA's warning letter database.
Our Picks, Ranked
Compounded semaglutide at $75/month and tirzepatide at $135/month are the lowest published figures across every provider we researched, and the reason is structural: OurView states its parent company is a licensed nationwide pharmacy, cutting out the usual telehealth-to-pharmacy markup. It covers all 50 states. Two caveats before you celebrate — those are starting-dose prices, and consultations are $97 unless you hold a membership whose cost OurView does not publish.
Pricing: Semaglutide from $75/month; consultation $97 or free with membership
Pros
- Lowest published compounded semaglutide price at $75/month
- Compounded tirzepatide from $135/month
- Parent company is a licensed nationwide pharmacy
- Available in all 50 states
Cons
- $97 consultation fee unless you hold a membership
- Membership cost is not published
- Quoted prices are for starting doses only
- Lab requirements, insurance and HSA/FSA acceptance are not published
Trimi is the cheapest program where the advertised number is genuinely the whole bill: $99/month for compounded semaglutide and $125 for tirzepatide covers medication, clinician visits, ongoing check-ins and free overnight shipping, with no membership stacked on top. It names its 503A pharmacies, covers all 50 states, and is FSA/HSA eligible. The catch is that those rates are quoted on annual plans.
Pricing: All-in from $99/month on an annual plan
Pros
- One flat fee covers medication, visits, check-ins and shipping
- Names its 503A partner pharmacies (VialsRx and GreenwichRx)
- Compounded semaglutide $99/month, tirzepatide $125/month
- Available in all 50 states
Cons
- Headline pricing is tied to annual plans
- Month-to-month pricing is not published
- Lab requirements are not published
- Cancellation and refund terms are not published
Compounded semaglutide starts at $74 for the first month with no separate membership fee — the lowest first-month cost we found. Crucially, OrderlyMeds publishes the renewal rate too ($149/month), so you can budget honestly rather than being surprised. It also names its compounding pharmacies and covers all 50 states. In June 2026 FDA issued OrderlyMeds a warning letter (MARCS-CMS 728291) over claims about compounded GLP-1 products on orderlymeds.com; read it before deciding.
Pricing: From $74 first month, $149/month thereafter
Pros
- Names its partner pharmacies rather than describing them vaguely
- Publishes both intro pricing and the ongoing rate
- Providers licensed in all 50 states
- No separate membership fee disclosed
Cons
- Price roughly doubles after the introductory month
- Lab requirements are not published
- Cancellation and refund terms are not published
- Does not accept insurance
Shapely
Insurance-billed visits with compounded GLP-1s from $99/month
At $99/month for compounded semaglutide with no introductory gimmick, Shapely is the cheapest program that also includes monthly video visits, monthly dietitian visits, a smart scale, $75 flat-rate labs and free 2-day shipping. Visits bill to insurance. The limitation is reach — California, Florida, New York and Texas only.
Pricing: Membership $99/month (promo $49) + medication from $99/month
Pros
- In network with Medicare and most PPO plans for visits
- Compounded semaglutide starts at $99/month
- Publishes dose-tiered medication pricing openly
- Flat $75 lab rate for uninsured patients
Cons
- Available in only four states
- $99/month membership required on top of medication
- Compounded medications are not reimbursed by insurance
- Cancellation and refund terms are not published
Compounded semaglutide/B3 starts at $129 per vial at 0.25mg with a free new patient consultation and just $49/month for medical care. Because Aspire publishes a price for every dose from 0.25mg to 2.4mg, it is the easiest program to model your real annual cost against. HSA and FSA cards are accepted.
Pricing: $49/month care + compounded medication from $129 per vial
Pros
- Publishes per-vial pricing at every dose level
- Free new patient consultation
- Low $49/month medical care fee
- HSA and FSA cards accepted for services and compounded medications
Cons
- Insurance not accepted for visits
- Consultation fees generally non-refundable once a provider has reviewed your case
- All medication sales are final once shipped
- Available in a limited set of states
Citizen Meds advertises tirzepatide at $145 and semaglutide at $125, both as steep markdowns from a higher list price, and displays LegitScript approval. Treat this one as price-first and verify-second: it does not state whether its medications are compounded or brand-name, does not describe its consultation process, and does not publish a pharmacy or states served. Get those answers in writing before ordering.
Pricing: Semaglutide $125/month; tirzepatide $145/month (discounted)
Pros
- Among the lowest advertised prices: semaglutide $125, tirzepatide $145
- LegitScript approved and PCCA member badges displayed
- Names its prescribing physicians
- No insurance required
Cons
- Does not state whether medications are compounded or brand-name
- Consultation process is not described
- Pharmacy is not named
- States served are not published
If the goal is the lowest possible monthly medication cost, Nurx's oral options are in a different bracket entirely — metformin at $15/month, topiramate at $15–$30, bupropion and naltrexone at $60, and Nurx 3-in-1 pills from $75, several potentially $0/month with insurance. Care is billed separately at $79 upfront plus $79/month.
Pricing: $79 consultation + $79/month care fee; orals from $15/month
Pros
- Full range of brand-name GLP-1 injectables available
- Low-cost oral options from $15/month, some $0 with insurance
- Proprietary 3-in-1 combination pills from $75/month
- Free shipping on pharmacy-fulfilled medications
Cons
- $79 consultation fee plus $79/month provider support fee, cash pay only
- Branded GLP-1s cannot be shipped by Nurx's pharmacy
- Brand-name injectables average $650-$1,300/month without coverage
- Not offered in every state
Oral semaglutide runs $179/month on sale and injections $149/month, with new patients offered $100 off the first month. FSA and HSA cards are accepted and shipping is free. The regular rates are $279 and $249, so confirm which you will be paying at renewal before committing.
Pricing: From $149/month (sale price; regularly $249)
Pros
- Injectable, oral and microdose GLP-1 formats all available
- Shows sale and regular pricing side by side
- FSA and HSA accepted for most patients
- Fast and free discreet shipping
Cons
- Does not accept insurance for weight-loss treatment
- Not a pharmacy — does not carry or ship medicines itself
- Available in most, but not all, U.S. states
- Lab requirements and refund terms are not published on the program page
Lemonaid's compounded semaglutide and tirzepatide microdose plans are $199/month against $299 for standard plans, and its 6-month tirzepatide plan drops to $229/month — the best long-commitment rate we found. A $49 membership applies and Lemonaid is cash-pay only, with no insurance accepted for any fee.
Pricing: Membership $49/month + medication from $199/month
Pros
- Publishes medication prices openly instead of requiring a quiz first
- Offers both compounded and brand-name GLP-1 options
- Lower-cost microdose plans at $199/month
- Multi-month plans reduce the monthly medication cost
Cons
- $49/month membership is charged on top of medication
- Cash-pay only — no insurance accepted for any fees
- Not yet available in all 50 states
- Does not publish its pharmacy partners or shipping cadence
Side-by-Side Comparison
| Provider | Rating | Pricing | Best for |
|---|---|---|---|
| OurView Health | 8.2/10 | Semaglutide from $75/month; consultation $97 or free with membership | Price-driven patients who want pharmacy-direct rates and will confirm the membership cost first |
| Trimi Health | 8.5/10 | All-in from $99/month on an annual plan | Patients who want a single all-inclusive price and are comfortable committing to an annual plan |
| OrderlyMeds | 8.3/10 | From $74 first month, $149/month thereafter | Patients who want to know exactly which pharmacy compounds their medication before ordering |
| Shapely | 8.6/10 | Membership $99/month (promo $49) + medication from $99/month | Patients in CA, FL, NY or TX who want insurance-billed visits, real dietitian support, and published prices |
| Aspire Health | 8.1/10 | $49/month care + compounded medication from $129 per vial | Cost-conscious patients who want to know what every dose step will cost before they titrate up |
| Citizen Meds | 7.4/10 | Semaglutide $125/month; tirzepatide $145/month (discounted) | Price-focused shoppers willing to get the missing details in writing before ordering |
| Nurx | 8.2/10 | $79 consultation + $79/month care fee; orals from $15/month | Patients who want brand-name GLP-1s billed to insurance, or a genuinely cheap oral alternative |
| 24hrdoc | 8/10 | From $149/month (sale price; regularly $249) | Patients who want an oral or microdose GLP-1 option and plan to pay with an FSA or HSA card |
| Lemonaid Health | 8.7/10 | Membership $49/month + medication from $199/month | Shoppers who want to compare compounded and brand-name GLP-1 pricing openly before starting |
Pricing in this category changes frequently and promotional rates often differ from renewal rates. Confirm current costs directly with each provider before enrolling.
The Three Costs Everyone Forgets
Advertised prices in this category are structured to look lower than what you will actually pay. Three things drive the difference:
- The renewal rate. OrderlyMeds moves from $74 to $149 on semaglutide and $149 to $299 on tirzepatide. 24hrdoc's sale prices of $149 and $239 are regularly $249 and $339. That is a $100–$150 monthly swing once the promotion ends.
- The membership fee. Medication price is rarely the whole bill. Expect $19.99/month at PlushCare, $49 at Lemonaid and Aspire, $74.99 at Ivím, $79 at Nurx and Hello Alpha, and $99 at Shapely. A $99 medication plus a $99 membership costs more than a $149 medication with no membership — which is why all-in programs like Trimi Health, and no-membership ones like Renlo Health and Good Life Meds, are worth comparing separately.
- Dose escalation. Compounded pricing usually scales with the amount of active ingredient. Shapely's semaglutide runs $99 at the starting dose, $139 at low-mid and $179 at high doses. Aspire's tirzepatide runs $149 at 2.5mg and $299 at 15mg. Budget for where you will end up.
What a Realistic Year Costs
Using published rates, here is roughly what twelve months looks like on a compounded semaglutide program, assuming you titrate to a mid-to-high dose:
- Lean setup — an all-in program at roughly $99/month, or a no-membership program at $149/month, lands near $1,200–$1,800 per year.
- Typical setup — $149–$179/month medication plus a $49–$75 membership lands near $2,400–$3,000 per year.
- Full-service setup — higher-dose medication plus a $99 membership with dietitian visits and labs lands near $3,300 per year.
- Brand-name without coverage — Ozempic at $1,199/month or Wegovy at $1,599/month exceeds $14,000 per year. This is the gap insurance is worth fighting for.
These are illustrative ranges built from published prices, not quotes. Your actual cost depends on your dose, your state, your plan length and any promotion running when you enroll.
Cheaper Does Not Always Mean Better Value
The lowest number on a page is not always the best deal. A few things worth paying for:
Included labs. Shapely offers a $75 flat rate and TrimRx bundles lab work into its plan. Paying for labs separately can easily exceed the monthly saving from a cheaper program.
Included shipping and supplies. Shapely includes shipping, syringes and alcohol pads. 24hrdoc and OrderlyMeds ship free. Those are real line items elsewhere.
Real clinician access. Ivím's unlimited 1:1 provider consults and Nurx's unlimited provider messaging matter most in the first months, when side effects are most likely. Our side effects timeline covers what to expect.
Sane refund terms. Paying $30 more per month at a program that refunds patients it cannot treat may beat a cheaper program that keeps your money.
Frequently Asked Questions
What is the cheapest GLP-1 program?
OurView Health publishes the lowest price at $75/month for compounded semaglutide, though consultations are $97 without a membership it does not price publicly. Trimi Health is cheapest all-in at $99/month covering medication, visits, check-ins and shipping. OrderlyMeds has the lowest first-month price at $74, rising to $149.
How much does a GLP-1 cost per month without insurance?
Compounded semaglutide generally runs $75–$299/month and compounded tirzepatide $125–$299/month at the providers we reviewed, plus membership fees of roughly $19–$99/month at most programs. Brand-name medication without coverage runs roughly $1,000–$1,840/month.
Are cheap compounded GLP-1s safe?
Price is not the safety variable — pharmacy quality and clinical oversight are. Compounded medications are not FDA-approved and the FDA does not evaluate their safety, effectiveness or quality. Favour providers that name their pharmacy or at minimum its 503A/503B category, and that give you real clinician access.
Can I use HSA or FSA money to lower my GLP-1 cost?
Often yes, and it is effectively a discount equal to your marginal tax rate. Ivím Health, Aspire Health, 24hrdoc, Doctronic, Trimi Health and Hello Alpha all state they accept HSA or FSA cards, and Medi-Weightloss says many of its locations welcome them. Confirm requirements with your plan administrator.
Do multi-month plans actually save money?
They can. Lemonaid Health's compounded tirzepatide drops from $299/month to $249 on a 3-month plan and $229 on a 6-month plan, and Shapely's 3-month packages run $297 total at low-mid doses. The trade-off is committing before you know how you tolerate the medication.
Is there anything cheaper than a GLP-1 for weight loss?
Yes. Nurx prices metformin at $15/month and topiramate at $15–$30/month, both potentially $0 with insurance, plus bupropion and naltrexone at $60/month and 3-in-1 combination pills from $75. These are different medications with different mechanisms and results — a clinician can tell you whether they suit your situation.
Medical Disclaimer: This guide is for educational and comparison purposes only and is not medical advice. Rx Saver Hub is not a medical provider and does not prescribe medication. Compounded medications are not FDA-approved, and the FDA does not evaluate their safety, effectiveness or quality. Rankings reflect our editorial assessment of publicly available information, including how much each provider discloses about pricing, pharmacies and clinical process. Always consult a qualified healthcare provider before starting, stopping or changing any weight-loss treatment. Individual results vary.