Best Semaglutide Providers Compared
Semaglutide is the most widely prescribed GLP-1 for weight loss, sold both as FDA-approved Wegovy and Ozempic and as cheaper compounded versions. The gap between those routes used to be enormous — around $99 a month against $1,600. It is not any more: Novo Nordisk now sells Wegovy and Ozempic direct at $149 a month for the pill, which changes the calculation for anyone who assumed brand-name was out of reach. Here is how the leading semaglutide programs actually compare.
The Quick Answer
Start with NovoCare Pharmacy — Novo Nordisk's own pharmacy sells FDA-approved Wegovy and Ozempic pills from $149/month and pens from $199, which is close enough to compounded pricing that the usual reason to choose compounded largely disappears. If you still want a compounded program, Trimi Health is the best all-in value at $99/month with named 503A pharmacies across all 50 states, yourEra starts at $79, and Shapely offers the strongest clinical package if you live in one of its four states. For Wegovy or Ozempic through insurance, use PlushCare or Hello Alpha.
Want tirzepatide instead? See our tirzepatide provider rankings.
FDA actions affecting providers on this page
FDA has issued warning letters to telehealth companies over false or misleading claims about compounded GLP-1 products. 3 providers ranked on this page received one. A warning letter is FDA's stated position that violations occurred — not a court finding, a recall, or a determination that any patient was harmed — and companies often correct the cited material.
- OrderlyMeds — FDA warning letter, June 8, 2026 (MARCS-CMS 728291). Read it on fda.gov →
- Ivím Health — FDA warning letter, February 20, 2026 (MARCS-CMS 721816). Read it on fda.gov →
- 24hrdoc — FDA warning letter, February 20, 2026 (MARCS-CMS 717984). Read it on fda.gov →
We keep these providers listed because their published details are still worth comparing, and we disclose the action so you can weigh it yourself. You can search any company in FDA's warning letter database.
Our Picks, Ranked
NovoCare Pharmacy
Novo Nordisk direct — Wegovy and Ozempic pills from $149/month
Novo Nordisk sells its own semaglutide direct, and it has repriced the category: the Wegovy or Ozempic pill starts at $149/month and pens at $199, against compounded programs charging $75–$299. That is FDA-approved medicine from the manufacturer, so authenticity and quality are not in question the way they are with compounding. Two caveats worth pricing in. Pill cost climbs with dose — $149 at 1.5mg, $199 at 4mg, $299 at 9mg and 25mg — and the $199 pen price is an introductory offer covering two fills through December 31, 2026, after which Wegovy is $349/month. NovoCare is a pharmacy, not a clinic, so you need a prescriber; it offers a telehealth referral if you do not have one.
Pricing: Pills from $149/month, pens from $199/month self-pay; as little as $25/month with eligible insurance
Pros
- $149/month is the lowest published cash price for an FDA-approved GLP-1
- Pill and pen formats for both Wegovy and Ozempic
- Free home delivery, with pharmacy pickup also available
- Insured patients may pay as little as $25/month for up to 3 months
Cons
- Pill pricing doubles as you titrate — $149 at 1.5 mg rises to $299 at 9 mg and 25 mg
- The $199 pen price is an introductory offer for 2 fills through December 31, 2026, then $349–$499/month
- Semaglutide only — no tirzepatide, so no Zepbound or Mounjaro equivalent
- No clinicians of its own; you must bring or arrange a prescription
Compounded semaglutide from $79/month with the telehealth visit, prescription and free shipping bundled in, and — importantly — the same price at every dose, so titrating up does not raise the bill. The clinician network covers all 50 states and members get unlimited messaging with the care team. yourEra is also unusually candid in its own FAQ, stating plainly that compounded drugs are not FDA-approved and that the FDA does not verify their safety, effectiveness or quality. It does not name its pharmacy partners, and cancellation terms are not published.
Pricing: Semaglutide from $79/month, tirzepatide from $159/month — visit and shipping included
Pros
- Semaglutide from $79/month, among the lowest published starting prices anywhere
- Same price at every dose — no escalation charges
- Telehealth visit, prescription and free shipping all included in the price
- Licensed clinician network covering all 50 states
Cons
- Compounded only — no brand-name route
- Fulfilment pharmacies are not named
- Cancellation and refund terms are not published
- The YourEra Optimum labs-and-coaching tier is still listed as coming soon
Compounded semaglutide at $99/month covers medication, clinician visits, ongoing check-ins and free overnight shipping in a single fee — no membership stacked on top, which makes it the cleanest number to compare in this category. Trimi also names its 503A pharmacies (VialsRx and GreenwichRx), covers all 50 states through the Arora Health clinical network, and is FSA/HSA eligible. The rate is quoted on an annual plan.
Pricing: All-in from $99/month on an annual plan
Pros
- One flat fee covers medication, visits, check-ins and shipping
- Names its 503A partner pharmacies (VialsRx and GreenwichRx)
- Compounded semaglutide $99/month, tirzepatide $125/month
- Available in all 50 states
Cons
- Headline pricing is tied to annual plans
- Month-to-month pricing is not published
- Lab requirements are not published
- Cancellation and refund terms are not published
At $75/month for compounded semaglutide at the starting dose, OurView publishes the lowest figure we found anywhere — enabled by its parent company being a licensed nationwide pharmacy. It covers all 50 states with a three-minute intake and a U.S.-licensed physician visit. Budget for the $97 consultation fee unless you take the membership, whose price OurView does not publish.
Pricing: Semaglutide from $75/month; consultation $97 or free with membership
Pros
- Lowest published compounded semaglutide price at $75/month
- Compounded tirzepatide from $135/month
- Parent company is a licensed nationwide pharmacy
- Available in all 50 states
Cons
- $97 consultation fee unless you hold a membership
- Membership cost is not published
- Quoted prices are for starting doses only
- Lab requirements, insurance and HSA/FSA acceptance are not published
Compounded semaglutide starts at $99/month with dose-tiered pricing published openly — $139 at low-mid doses and $179 at high doses — so there are no surprises when you titrate up. Visits run through insurance, labs are $75 flat if you are uninsured, and shipping, syringes and alcohol pads are included. Available in California, Florida, New York and Texas only.
Pricing: Membership $99/month (promo $49) + medication from $99/month
Pros
- In network with Medicare and most PPO plans for visits
- Compounded semaglutide starts at $99/month
- Publishes dose-tiered medication pricing openly
- Flat $75 lab rate for uninsured patients
Cons
- Available in only four states
- $99/month membership required on top of medication
- Compounded medications are not reimbursed by insurance
- Cancellation and refund terms are not published
Compounded semaglutide starts at $74 for the first month and $149/month thereafter, and OrderlyMeds is unusually specific about who compounds it — SmartPharmaRx, Casa and PerfectionRx/PerfectRx, described as 503A pharmacies led by credentialed pharmacists. Providers are licensed in all 50 states and no separate membership fee is charged. In June 2026 FDA issued OrderlyMeds a warning letter (MARCS-CMS 728291) over claims about compounded GLP-1 products on orderlymeds.com; read it before deciding.
Pricing: From $74 first month, $149/month thereafter
Pros
- Names its partner pharmacies rather than describing them vaguely
- Publishes both intro pricing and the ongoing rate
- Providers licensed in all 50 states
- No separate membership fee disclosed
Cons
- Price roughly doubles after the introductory month
- Lab requirements are not published
- Cancellation and refund terms are not published
- Does not accept insurance
Compounded semaglutide/B3 is priced per vial from $129 at 0.25mg up to $189 at 2.4mg, so the full cost of titration is visible before you begin. The new patient consultation is free, monthly medical care is $49, and HSA/FSA cards are accepted for both services and compounded medication.
Pricing: $49/month care + compounded medication from $129 per vial
Pros
- Publishes per-vial pricing at every dose level
- Free new patient consultation
- Low $49/month medical care fee
- HSA and FSA cards accepted for services and compounded medications
Cons
- Insurance not accepted for visits
- Consultation fees generally non-refundable once a provider has reviewed your case
- All medication sales are final once shipped
- Available in a limited set of states
Compounded semaglutide starts at $149/month on top of a $74.99 membership, but that membership includes unlimited 1:1 provider consults, 24/7 care team access and functional nutritional counseling. Ivím states plainly that compounded semaglutide is not FDA-approved and not covered by insurance, while confirming HSA/FSA cards work.
Pricing: Membership $74.99/month + compounded semaglutide from $149/month
Pros
- Compounded semaglutide starts at $149/month
- Free initial provider consultation
- Unlimited 1:1 provider consults included in membership
- HSA and FSA cards accepted
Cons
- $74.99/month membership is among the higher fees in this category
- Compounded semaglutide is not covered by insurance
- Lab requirements, shipping details and states served are not published
- Refund terms are behind a policy link rather than stated on the page
Lemonaid Health
Brand-name and compounded GLP-1s with published price tiers
Lemonaid is the most complete semaglutide shelf here: compounded semaglutide at $299/month ($249 on the 3-month plan), microdoses at $199/month, and brand-name Ozempic at $1,199/month or Wegovy at $1,599/month — all published up front. A $49 membership applies and the service is cash-pay only.
Pricing: Membership $49/month + medication from $199/month
Pros
- Publishes medication prices openly instead of requiring a quiz first
- Offers both compounded and brand-name GLP-1 options
- Lower-cost microdose plans at $199/month
- Multi-month plans reduce the monthly medication cost
Cons
- $49/month membership is charged on top of medication
- Cash-pay only — no insurance accepted for any fees
- Not yet available in all 50 states
- Does not publish its pharmacy partners or shipping cadence
Brello advertises compounded semaglutide with B6 at a $133 per month special, with a 3-month plan cut from $599 to $399 — among the lowest we found. Read the structure carefully first: Brello takes payment before you complete the medical intake, and refunds are available only within 24 hours of provider review, minus a $50 professional services fee.
Pricing: $133/month special; 3-month plan $399
Pros
- Among the lowest advertised compounded semaglutide prices at $133/month
- 3-month plan discounted from $599 to $399
- Includes app support, virtual fitness and nutrition classes
- Cancel at any time
Cons
- You pay before completing the medical intake form
- Refunds carry a $50 professional services fee
- Refund window is only 24 hours after provider review
- States served are not listed on the product page
24hrdoc offers semaglutide as weekly injections at $149/month on sale, oral semaglutide as dissolvable tablets or drops at $179/month, and a separate clinically supervised microdosing protocol. FSA and HSA cards are accepted, shipping is free and discreet, and reviews are same-day with no commitment required.
Pricing: From $149/month (sale price; regularly $249)
Pros
- Injectable, oral and microdose GLP-1 formats all available
- Shows sale and regular pricing side by side
- FSA and HSA accepted for most patients
- Fast and free discreet shipping
Cons
- Does not accept insurance for weight-loss treatment
- Not a pharmacy — does not carry or ship medicines itself
- Available in most, but not all, U.S. states
- Lab requirements and refund terms are not published on the program page
If you want FDA-approved Wegovy or Ozempic rather than a compounded version, PlushCare runs a full obesity lab panel — CBC, CMP, lipids, A1C, TSH and insulin — and pursues prior authorization with your insurer. In-network patients often pay $30 or less per visit, and PlushCare refunds anyone it cannot treat.
Pricing: Membership $19.99/month (first month free); $129 initial visit without insurance
Pros
- Pursues insurance coverage and prior authorization for brand-name GLP-1s
- Runs a comprehensive obesity lab panel before prescribing
- Most in-network patients pay $30 or less per visit
- Full refund if PlushCare is unable to treat you
Cons
- Out-of-pocket brand-name cost is roughly $1,000/month without coverage
- $129 initial visit without insurance
- Prior authorization adds time before treatment starts
- Pharmacy, shipping and state coverage are not published on the GLP-1 page
Side-by-Side Comparison
| Provider | Rating | Pricing | Best for |
|---|---|---|---|
| NovoCare Pharmacy | 9.2/10 | Pills from $149/month, pens from $199/month self-pay; as little as $25/month with eligible insurance | Anyone who wants FDA-approved semaglutide at the lowest published cash price, especially in oral form |
| yourEra | 8/10 | Semaglutide from $79/month, tirzepatide from $159/month — visit and shipping included | Price-sensitive patients who want the visit bundled in and a rate that will not move as they titrate |
| Trimi Health | 8.5/10 | All-in from $99/month on an annual plan | Patients who want a single all-inclusive price and are comfortable committing to an annual plan |
| OurView Health | 8.2/10 | Semaglutide from $75/month; consultation $97 or free with membership | Price-driven patients who want pharmacy-direct rates and will confirm the membership cost first |
| Shapely | 8.6/10 | Membership $99/month (promo $49) + medication from $99/month | Patients in CA, FL, NY or TX who want insurance-billed visits, real dietitian support, and published prices |
| OrderlyMeds | 8.3/10 | From $74 first month, $149/month thereafter | Patients who want to know exactly which pharmacy compounds their medication before ordering |
| Aspire Health | 8.1/10 | $49/month care + compounded medication from $129 per vial | Cost-conscious patients who want to know what every dose step will cost before they titrate up |
| Ivím Health | 8.4/10 | Membership $74.99/month + compounded semaglutide from $149/month | Patients who want heavy clinician contact and nutrition support alongside affordable compounded medication |
| Lemonaid Health | 8.7/10 | Membership $49/month + medication from $199/month | Shoppers who want to compare compounded and brand-name GLP-1 pricing openly before starting |
| Brello Health | 7.6/10 | $133/month special; 3-month plan $399 | Price-driven shoppers comfortable paying up front and reading the refund terms closely first |
| 24hrdoc | 8/10 | From $149/month (sale price; regularly $249) | Patients who want an oral or microdose GLP-1 option and plan to pay with an FSA or HSA card |
| PlushCare | 8.5/10 | Membership $19.99/month (first month free); $129 initial visit without insurance | Patients with insurance who want brand-name GLP-1s covered and proper lab work before starting |
Pricing in this category changes frequently and promotional rates often differ from renewal rates. Confirm current costs directly with each provider before enrolling.
Semaglutide Prices at a Glance
These are the published monthly costs for compounded semaglutide across the providers we researched, as stated on each provider's own site:
- OrderlyMeds — $74 first month, then $149/month
- OurView Health — $75/month at the starting dose, plus a $97 consultation without membership
- Trimi Health — $99/month all-in on an annual plan, no separate membership
- Shapely — from $99/month, $139 at low-mid doses, $179 at high doses
- Citizen Meds — $125/month advertised, marked down from $299
- Aspire Health — $129–$189 per vial by dose, plus $49/month care
- Brello Health — $133/month special; 3-month plan $399
- Ivím Health — from $149/month plus $74.99 membership
- 24hrdoc — $149/month on sale (regularly $249); oral $179/month
- Call-On-Doc — $250 with home delivery
- Lemonaid Health — $299/month, $249 on the 3-month plan; microdoses $199
- Renlo Health and Good Life Meds — no membership fee, but neither publishes a medication price
Brand-name semaglutide through a telehealth reseller is a different universe: Lemonaid lists Ozempic at $1,199/month and Wegovy at $1,599/month, OrderlyMeds lists Wegovy at $1,839/month, and altRx lists Wegovy at $1,579 and Ozempic at $1,149.
Do not pay those prices. Novo Nordisk sells the same FDA-approved medicine directly through NovoCare Pharmacy: the Wegovy or Ozempic pill from $149/month and pens from $199. Buying brand-name semaglutide from a reseller now costs several times the manufacturer's own price for an identical product. If you want brand-name, go direct or use insurance — the reseller markup no longer buys you anything except a prescriber, and a $75 telehealth visit gets you that.
Injectable vs Oral Semaglutide
Most semaglutide is injected once weekly, but oral options have expanded considerably and are worth knowing about if needles are a barrier.
24hrdoc offers oral semaglutide as dissolvable tablets or drops at $179/month. Klinic specialises in the oral route, offering compounded oral semaglutide formulated with ondansetron to blunt nausea alongside FDA-approved Oral Wegovy, and verifies your insurance before matching you with a provider. Ivím Health carries the Wegovy and Foundayo pills.
Oral and injectable semaglutide are not dose-equivalent, and absorption differs. Which is appropriate for you is a clinical decision — read our oral vs injectable GLP-1 comparison and then discuss it with a prescriber.
What About Semaglutide Microdosing?
Several providers now sell lower-dose semaglutide plans at a discount — Lemonaid offers compounded semaglutide microdoses at $199/month versus $299 for its standard plan, and 24hrdoc runs a separate clinically guided low-dose GLP-1 microdosing protocol supervised by licensed providers.
The appeal is lower cost and potentially milder side effects. The caveat is that microdosing protocols are not what the pivotal weight-loss trials studied, so expected results are less well characterised. Treat it as a conversation to have with a prescriber rather than a default choice, and be clear about what dose you are actually receiving.
Frequently Asked Questions
Who has the cheapest compounded semaglutide?
OurView Health publishes the lowest ongoing price at $75/month at the starting dose, though consultations are $97 without a membership. OrderlyMeds has the lowest first month at $74, rising to $149. Trimi Health is cheapest all-in at $99/month with no separate fees. Always confirm the renewal rate and the price at your maintenance dose, not just the introductory one.
Is compounded semaglutide as effective as Wegovy?
There is no equivalence claim you can rely on. Compounded semaglutide is not FDA-approved, and the FDA does not evaluate its safety, effectiveness or quality — several providers, including Ivím Health and Brello Health, state this directly on their own pages. Wegovy is FDA-approved and studied in registration trials. Discuss the difference with a licensed clinician.
Do I need lab work to start semaglutide?
It depends entirely on the provider. PlushCare runs a full obesity panel covering CBC, CMP, lipids, A1C, TSH and insulin. Shapely strongly recommends recent labs but does not require them, offering a $75 flat rate for uninsured patients. Many compounded-focused providers do not publish any lab requirement at all.
Can I use HSA or FSA funds for semaglutide?
Often yes, even when insurance will not cover compounded medication. Ivím Health, Aspire Health, 24hrdoc and Doctronic all state they accept HSA or FSA cards. Confirm with your plan administrator, since eligibility can depend on having a letter of medical necessity.
How much does brand-name semaglutide cost without insurance?
It depends entirely on where you buy it. Through a telehealth reseller, roughly $1,150–$1,840 per month — Lemonaid lists Ozempic at $1,199 and Wegovy at $1,599, OrderlyMeds lists Wegovy at $1,839. Direct from the manufacturer via NovoCare Pharmacy, the same FDA-approved medicine is $149/month for the pill and $199 for pens. Always check the manufacturer-direct price before paying a reseller.
Which semaglutide providers ship nationwide?
OrderlyMeds states its providers are licensed in all 50 states, and Call-On-Doc and Klinic both list coverage across all 50 states plus DC. Shapely is limited to California, Florida, New York and Texas, and Rixa Health serves eight states. Check availability before you pay.
Medical Disclaimer: This guide is for educational and comparison purposes only and is not medical advice. Rx Saver Hub is not a medical provider and does not prescribe medication. Compounded medications are not FDA-approved, and the FDA does not evaluate their safety, effectiveness or quality. Rankings reflect our editorial assessment of publicly available information, including how much each provider discloses about pricing, pharmacies and clinical process. Always consult a qualified healthcare provider before starting, stopping or changing any weight-loss treatment. Individual results vary.