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#116

TMates Review

Semaglutide in injection or oral form, four plan lengths

7.5/10
Good
7.5/10

Not published publicly — plan pricing appears during intake

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Overview

TMates runs a broad telehealth catalogue — GLP-1s, TRT, ED, NAD+, hair loss for men and women, and non-GLP-1 weight options — with its semaglutide programme offered as either a once-weekly injection or an oral form, depending on what the prescriber recommends. Plans come in one, three, six and twelve-month lengths, which is a sensible structure that lets patients trade commitment against price. The product page is unusually candid about side effects, noting nausea that typically subsides after two to four weeks rather than glossing over it. The problem for a prospective patient is that TMates does not render its pricing to public review, so the actual cost of each plan length cannot be compared before starting intake — and the plan-length structure means that difference could be substantial.

Pros

  • Both once-weekly injection and oral semaglutide options
  • Four plan lengths — one, three, six and twelve months
  • Doctor-supervised programme rather than prescription-only
  • Candid about side effects, including the nausea timeline
  • Broad catalogue covering GLP-1s, TRT, ED, NAD+ and hair loss
  • Women's hair loss covered as well as men's

Cons

  • Pricing does not render publicly, so plans cannot be compared before intake
  • Compounding pharmacy is not named
  • No published state availability list
  • Cancellation and refund terms not published
  • Compounded medications are not FDA-approved as finished products

Key Features

Compounded Semaglutide, Injection or Oral
1, 3, 6 and 12-Month Plans
Doctor-Supervised Programme
TRT, ED, NAD+ and Hair Loss
Once-Weekly Dosing

Best For

Patients who specifically want an oral semaglutide option and are willing to complete intake to see pricing

TMates at a Glance

Everything below reflects what TMates published on its own site as of August 24, 2026. Where a detail is not published, we say so rather than guessing.

Medications offered
  • Compounded semaglutide (injection)
  • Oral semaglutide option
  • Testosterone replacement therapy
  • ED treatments
  • NAD+
  • Men's and women's hair loss treatment
Brand-name or compounded
Compounded. TMates describes its semaglutide as compounded and explains what that means on the product page. Compounded medications are not FDA-approved as finished products.
Consultation process
Online intake with provider review. Treatment is taken as a once-weekly injection or an oral option depending on the prescriber's recommendation, across plan lengths of one, three, six or twelve months.
Eligibility
Not published on TMates's website at the time of review. Confirm directly with TMates before enrolling.
Provider involvement
Described as a doctor-supervised programme with personalised dosing. Individual prescribers are not named on the pages reviewed.
Lab requirements
Not published on TMates's website at the time of review. Confirm directly with TMates before enrolling.
Pharmacy fulfillment
Not published on TMates's website at the time of review. Confirm directly with TMates before enrolling.
Shipping
Not published on TMates's website at the time of review. Confirm directly with TMates before enrolling.

Pricing

TMates offers one, three, six and twelve-month plan lengths but does not render pricing to public review, so per-plan costs cannot be compared before intake. Ask for the monthly figure at each plan length, and specifically what the ongoing rate is rather than a first-month promotional price.

Membership fees

Not published on TMates's website at the time of review. Confirm directly with TMates before enrolling.

Medication fees

  • Plan pricing not publicly rendered — obtain at intake

Prices change often in this category. Always confirm the current cost — including what you will pay after any introductory or promotional period — directly with TMates before enrolling.

Cancellation, Refunds & Payment

Cancellation policy
Not published on TMates's website at the time of review. Confirm directly with TMates before enrolling.
Refund policy
Not published on TMates's website at the time of review. Confirm directly with TMates before enrolling.
Insurance
Not published on TMates's website at the time of review. Confirm directly with TMates before enrolling.
HSA / FSA
Not published on TMates's website at the time of review. Confirm directly with TMates before enrolling.

Support Services

Doctor supervision across the programme
Multi-category catalogue on one account

Limitations to Know

  • No public pricing, preventing comparison before intake
  • Pharmacy, states, labs, cancellation and refund terms unpublished
  • Compounded products are not FDA-approved as finished drugs

Alternatives to TMates

Independent Wellness

Oral sublingual semaglutide and tirzepatide with fully published, locked pricing.

24hrdoc

Oral semaglutide as tablets or drops with pricing published up front.

PlexusDx

Daily oral tablet option with all-inclusive published pricing and six named pharmacies.

Still comparing? See our full ranking of online GLP-1 providers.

TMates FAQs

How much does TMates cost?

Pricing does not render on its public pages, so cost only becomes visible during intake. It offers one, three, six and twelve-month plan lengths — ask for the monthly figure at each, and confirm the ongoing rate rather than a first-month promotional price.

Does TMates offer oral semaglutide?

Yes. Treatment is taken as a once-weekly injection or an oral option depending on what the prescriber recommends, which is useful for people who would rather not inject.

Are TMates medications FDA-approved?

No. Its semaglutide is compounded, which TMates explains on the product page. Compounded medications are not reviewed by the FDA for safety, effectiveness or manufacturing quality as finished products.

What side effects does TMates warn about?

Its product page notes nausea, stating it typically subsides after two to four weeks. Being specific about the timeline rather than vague about side effects is a point in its favour.

Date reviewed: August 24, 2026

Sources consulted

Medical disclaimer: This review is for educational and comparison purposes only and is not medical advice. Rx Saver Hub is not a medical provider and does not prescribe medication. Compounded medications are not FDA-approved, and the FDA does not evaluate their safety, effectiveness or quality. Program details, pricing and availability change frequently — verify everything directly with TMates. Always consult a qualified healthcare provider before starting, stopping or changing any weight-loss treatment. Individual results vary.

TMates

7.5/10

Not published publicly — plan pricing appears during intake

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Compounded — not FDA-approved

Quick Stats

Rank#116 of 133
Rating7.5/10
PricingNot published publicly — plan pricing appears during intake

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